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Recombinant Rat Nuclear receptor subfamily 4 group A member 1 (Nr4a1)
SPP-03976
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Rattus norvegicus |
| Target Name | Nur77 |
| UniProt No. | P22829 |
| Subcellular Location | Cytoplasm, Nucleus |
| Tissue Specificity | Expressed in lung, brain and superior cervical ganglia. High levels are seen in the adrenal tissue. |
| Gene Abbr. | Nr4a1 |
| Full Name | nuclear receptor subfamily 4, group A, member 1 |
| Alias | HMR, Ngfi-b, Nur77 |
| Introduction | Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity). |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.