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Recombinant Rat Disks large homolog 1 (Dlg1), partial
SPP-01505
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Rattus norvegicus |
| Target Name | DLG1 |
| UniProt No. | Q62696 |
| Subcellular Location | Membrane, Peripheral membrane protein, Basolateral cell membrane, Endoplasmic reticulum membrane, Cell junction, synapse, postsynaptic cell membrane, postsynaptic density, Cell junction, synapse, Cell membrane, sarcolemma, Cell junction, Cytoplasm, Apical cell membrane |
| Tissue Specificity | Widely expressed. Strongly expressed in epithelial cells, in the small intestine it is only detected in the vili. Expressed in brain, heart (at protein level), muscle, lung and liver. In the brain it was detected in olfactory bulbs, cerebral cortex. |
| Gene Abbr. | Dlg1 |
| Full Name | discs large MAGUK scaffold protein 1 |
| Alias | Dlgh1, SAP97 |
| Introduction | Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.