Recombinant Rat Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe (Lfng), partial - CD BioSciences

service-banner

Recombinant Rat Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe (Lfng), partial

Recombinant Rat Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe (Lfng), partial

SPP-03595

Size Price
20 μg Online Inquiry
100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Rattus norvegicus
Target Name Lunatic Fringe
UniProt No. Q924T4
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Gene Abbr. Lfng
Full Name LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Introduction Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. Decreases the binding of JAG1 to NOTCH2 but not that of DLL1. Essential mediator of somite segmentation and patterning.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.