Recombinant Rat Apoptosis regulator BAX (Bax) - CD BioSciences

service-banner

Recombinant Rat Apoptosis regulator BAX (Bax)

Recombinant Rat Apoptosis regulator BAX (Bax)

SPP-00570

Size Price
20 μg Online Inquiry
100 μg Online Inquiry
Target Information
Species Rattus norvegicus
Target Name BAX
UniProt No. Q63690
Subcellular Location Isoform Alpha: Mitochondrion outer membrane, Single-pass membrane protein, Cytoplasm
Tissue Specificity Expressed in a wide variety of tissues, with highest levels in the testis and ovary.
Gene Abbr. BAX
Full Name BCL2 associated X, apoptosis regulator
Introduction Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.