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Recombinant Rat Activin receptor type-1C (Acvr1c)
SPP-00109
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
Target Information | |
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Species | Rattus norvegicus |
Target Name | Activin Receptor |
UniProt No. | P70539 |
Subcellular Location | Membrane, Single-pass type I membrane protein |
Tissue Specificity | Expressed in brain, kidney, lung, liver, testis, ovary, adrenal gland, heart, prostate, gastrointestinal tract, and spleen. Distributed throughout both adult and embryonic central nervous system and pancreatic islet cells. |
Gene Abbr. | Acvr1c |
Full Name | activin A receptor type 1C |
Alias | Alk-7, Alk7, habrec1 |
Introduction | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. |
Product Details | |
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Product Type | Recombinant Protein |
Storage & Handling | |
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Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.