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Recombinant Pig Presenilin-2 (PSEN2), partial
SPP-04387
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Sus scrofa |
| Target Name | presenilin 2 |
| UniProt No. | Q0MS45 |
| Subcellular Location | Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein |
| Tissue Specificity | Detected in the embryonic brain in frontal cortex (at protein level). Expressed in the developing brain: frontal cortex, cerebellum, hippocampus, basal ganglia and brain stem. Localized mainly in neuronal cells and astrocytes. |
| Gene Abbr. | PSEN2 |
| Full Name | presenilin 2 |
| Introduction | Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins (By similarity). |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.