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Recombinant Mouse Vesicle-associated membrane protein 8 (Vamp8), partial
SPP-05279
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | VAMP-8 |
| UniProt No. | O70404 |
| Subcellular Location | Lysosome membrane, Single-pass type IV membrane protein, Late endosome membrane, Single-pass type IV membrane protein, Early endosome membrane, Single-pass type IV membrane protein, Cell membrane, Single-pass type IV membrane protein |
| Tissue Specificity | Expressed abundantly in the kidney, less in the liver, brain, kidney, heart, lung, pancreas and placenta. |
| Gene Abbr. | Vamp8 |
| Full Name | vesicle-associated membrane protein 8 |
| Alias | AU041171, Edb, endo, endobrevin |
| Introduction | VAMP-8 (vesicle associated membrane protein 8; also endobrevin) is a 12 kDa member of the synaptobrevin family of proteins. It is a type IV transmembrane (TM) protein (i.e.- a type II TM protein whose C-terminus is predominately transmembrane) that is found in cells involved in vesicle release (platelets, mast cells and pancreatic acinar cells). It regulates exocytosis and decouples granule release from cytokine release. Human VAMP-8 is 100 amino acids (aa) in length. It contains a vSNARE coiled-coil homology region (aa 12-72) and a membrane-anchor domain (aa 76‑96). Over aa 1‑75, human VAMP-8 shares 93% aa identity with mouse VAMP‑2. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.