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Recombinant Mouse Tumor protein p53-inducible nuclear protein 2 (Tp53inp2)
SPP-05186
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | TP53INP2 |
| UniProt No. | Q8CFU8 |
| Subcellular Location | Cytoplasm, cytosol, Nucleus, Nucleus, PML body, Cytoplasmic vesicle, autophagosome |
| Gene Abbr. | Trp53inp2 |
| Full Name | transformation related protein 53 inducible nuclear protein 2 |
| Alias | 1110029F20Rik, Tp53, Tp53inp2 |
| Introduction | Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.