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Recombinant Mouse Signal transducing adapter molecule 2 (Stam2)
SPP-04932
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | STAM2 |
| UniProt No. | O88811 |
| Subcellular Location | Cytoplasm, Early endosome membrane, Peripheral membrane protein, Cytoplasmic side |
| Tissue Specificity | Ubiquitously expressed, with highest levels in testis. |
| Gene Abbr. | Stam2 |
| Full Name | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| Alias | 1200004O12Rik, 5730456G07Rik, BB145015, Hb, Hbp |
| Introduction | Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.