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Recombinant Mouse Putative sodium-coupled neutral amino acid transporter 9 (Slc38a9), partial
SPP-04818
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | SLC38A9 |
| UniProt No. | Q8BGD6 |
| Subcellular Location | Lysosome membrane, Multi-pass membrane protein, Late endosome membrane, Multi-pass membrane protein |
| Gene Abbr. | Slc38a9 |
| Full Name | solute carrier family 38, member 9 |
| Alias | 4833412L08Rik, 6720411P22Rik, 9130023D20Rik, 9430067K09Rik, A730092C09 |
| Introduction | Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead. The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.