Recombinant Mouse Partitioning defective 3 homolog (Pard3), partial - CD BioSciences

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Recombinant Mouse Partitioning defective 3 homolog (Pard3), partial

Recombinant Mouse Partitioning defective 3 homolog (Pard3), partial

SPP-04082

Size Price
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100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Mus musculus
Target Name PARD3
UniProt No. Q99NH2
Subcellular Location Cytoplasm, Endomembrane system, Cell junction, Cell junction, tight junction, Cell junction, adherens junction, Cytoplasm, cell cortex, Cytoplasm, cytoskeleton, Cell membrane
Tissue Specificity All isoforms are expressed in heart, while expression in brain is mainly limited to isoform 1, and to isoform 3 to a weaker level.
Gene Abbr. Pard3
Full Name par-3 family cell polarity regulator
Alias AA960621, AI256638, Asip, D8Ertd580, D8Ertd580e
Introduction Adapter protein involved in asymmetrical cell division and cell polarization processes (By similarity). Seems to play a central role in the formation of epithelial tight junctions (By similarity). Targets the phosphatase PTEN to cell junctions (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.