Recombinant Mouse Nuclear receptor subfamily 4 group A member 1 (Nr4a1) - CD BioSciences

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Recombinant Mouse Nuclear receptor subfamily 4 group A member 1 (Nr4a1)

Recombinant Mouse Nuclear receptor subfamily 4 group A member 1 (Nr4a1)

SPP-03975

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Target Information
Species Mus musculus
Target Name Nur77
UniProt No. P12813
Subcellular Location Cytoplasm, Nucleus
Tissue Specificity Highest levels occur in the testis followed by brain and muscle tissue.
Gene Abbr. Nr4a1
Full Name nuclear receptor subfamily 4, group A, member 1
Alias GFR, GFRP1, Gf, Gfrp, Hbr
Introduction Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity).
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.