Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 1 (Nfatc1) - CD BioSciences

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Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 1 (Nfatc1)

Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 1 (Nfatc1)

SPP-03818

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100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Mus musculus
Target Name NFAT2
UniProt No. O88942
Subcellular Location Cytoplasm, Nucleus
Tissue Specificity Expressed in spleen, lung, skeletal muscle, thymus and skin (PubMed:9388475). Weakly expressed in heart, brain, liver and kidney. Not expressed in testis (PubMed:10072529).
Gene Abbr. NFATC1
Full Name nuclear factor of activated T cells 1
Introduction Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (By similarity). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.