Recombinant Mouse Nicastrin (Ncstn) - CD BioSciences

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Recombinant Mouse Nicastrin (Ncstn)

Recombinant Mouse Nicastrin (Ncstn)

SPP-03876

Size Price
20 μg Online Inquiry
100 μg Online Inquiry
Target Information
Species Mus musculus
Target Name Nicastrin
UniProt No. P57716
Subcellular Location Membrane, Single-pass type I membrane protein, Cytoplasmic vesicle membrane, Single-pass type I membrane protein, Melanosome
Gene Abbr. Ncstn
Full Name nicastrin
Alias 9430068N19Rik, AA727311, Aph2, D1Dau13, D1Dau13e
Introduction Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.