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Recombinant Mouse Lymphoid enhancer-binding factor 1 (Lef1)
SPP-03513
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | LEF1 |
| UniProt No. | P27782 |
| Subcellular Location | Nucleus |
| Tissue Specificity | Lymphocytes. Found in distinct epithelial cell compartments of the skin and is abundant in the hair-producing progenitors of the follicle. |
| Gene Abbr. | Lef1 |
| Full Name | lymphoid enhancer binding factor 1 |
| Alias | 3000002B05, AI451430, Lef-, Lef-1 |
| Introduction | Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (By similarity). Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIASG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.