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Recombinant Mouse Interleukin-4 receptor subunit alpha (Il4r)
SPP-02946
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | IL-4 Receptor |
| UniProt No. | P16382 |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein; Isoform 2: Secreted |
| Tissue Specificity | Expressed in both Th1 and Th2 cells. |
| Gene Abbr. | Il4ra |
| Full Name | interleukin 4 receptor, alpha |
| Alias | CD124, I, Il4r |
| Introduction | Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.