Recombinant Mouse Interleukin-1 beta (Il1b) (Active) - CD BioSciences

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Recombinant Mouse Interleukin-1 beta (Il1b) (Active)

Recombinant Mouse Interleukin-1 beta (Il1b) (Active)

SPP-02610

Size Price
1 mg Online Inquiry
500 μg Online Inquiry
50 μg Online Inquiry
10 μg Online Inquiry
Target Information
Species Mus musculus
Target Name IL-1
UniProt No. P10749
Subcellular Location Cytoplasm, cytosol, Lysosome, Secreted, exosome, Cytoplasmic vesicle, autophagosome, Secreted
Tissue Specificity Expressed in activated macrophages (at protein level).
Gene Abbr. Il1b
Full Name interleukin 1 beta
Alias IL-, IL-1beta, Il-1b
Introduction IL-1 is a name that designates two proteins, IL-1 alpha and IL-1 beta, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-beta, designated interleukin 1 beta -converting enzyme (ICE), has been described. Mature human and mouse IL-1 beta share approximately 75% amino acid sequence identity and human IL-1 beta has been found to be active on murine cell lines.
Product Details
Product Type Recombinant Protein
Product Form Lyophilized powder
Buffer before Lyophilization Lyophilized from a 0.2 μm filtered 50 mM Tris-HCl, 50 mM NaCl, pH 8.0.
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

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