Online Inquiry
Recombinant Mouse Granzyme B (G, H) (Gzmb)
SPP-02314
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
500 μg | Online Inquiry |
Target Information | |
---|---|
Species | Mus musculus |
Target Name | GZMB |
UniProt No. | P04187 |
Subcellular Location | Cytoplasmic granule |
Gene Abbr. | Gzmb |
Full Name | granzyme B |
Alias | AI553453, CCP, CCP-1/C1, CCP-1/C11, CCP1 |
Introduction | This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). |
Product Details | |
---|---|
Product Type | Recombinant Protein |
Storage & Handling | |
---|---|
Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.