Recombinant Mouse Granzyme B (G, H) (Gzmb) - CD BioSciences

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Recombinant Mouse Granzyme B (G, H) (Gzmb)

Recombinant Mouse Granzyme B (G, H) (Gzmb)

SPP-02314

Size Price
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100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Mus musculus
Target Name GZMB
UniProt No. P04187
Subcellular Location Cytoplasmic granule
Gene Abbr. Gzmb
Full Name granzyme B
Alias AI553453, CCP, CCP-1/C1, CCP-1/C11, CCP1
Introduction This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity).
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.