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Recombinant Mouse Gamma-secretase subunit APH-1B (Aph1b)
SPP-00241
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | APH1B |
| UniProt No. | Q8C7N7 |
| Subcellular Location | Membrane, Multi-pass membrane protein |
| Gene Abbr. | Aph1b |
| Full Name | aph1 homolog B, gamma secretase subunit |
| Alias | 2310057K14Rik, Aph1c |
| Introduction | Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A (By similarity). |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.