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Recombinant Mouse Gamma-aminobutyric acid receptor-associated protein-like 2 (Gabarapl2)
SPP-02129
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | GABARAPL2 |
| UniProt No. | P60521 |
| Subcellular Location | Golgi apparatus, Cytoplasmic vesicle, autophagosome |
| Tissue Specificity | Ubiquitous. A high level expression is seen in brain, thymus, lung, heart, liver and kidney. |
| Gene Abbr. | Gabarapl2 |
| Full Name | gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 |
| Alias | 0610012F20Rik, 2900019O08Rik, AI173605, GATE-1, GATE-16 |
| Introduction | Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.