Recombinant Mouse Disheveled-associated activator of morphogenesis 1 (Daam1), partial - CD BioSciences

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Recombinant Mouse Disheveled-associated activator of morphogenesis 1 (Daam1), partial

Recombinant Mouse Disheveled-associated activator of morphogenesis 1 (Daam1), partial

SPP-01453

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100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Mus musculus
Target Name DAAM1
UniProt No. Q8BPM0
Subcellular Location Cytoplasm, Cytoplasm, cytoskeleton, cilium basal body
Tissue Specificity In early embryogenesis, expressed in embryonic and extraembryonic ectoderm. In later stages of gastrulation, expressed also in somites and ribs and posterior vertebrae of developing skeletal system.
Gene Abbr. Daam1
Full Name dishevelled associated activator of morphogenesis 1
Introduction Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments (By similarity). Involved in building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity).
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

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