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Recombinant Mouse Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe (Lfng)
SPP-03593
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Mus musculus |
| Target Name | Lunatic Fringe |
| UniProt No. | O09010 |
| Subcellular Location | Golgi apparatus membrane, Single-pass type II membrane protein |
| Tissue Specificity | Detected at 12.5 dpc in all tissues examined with the highest level observed in adult brain and spleen. Detected in the dental epithelium. |
| Gene Abbr. | Lfng |
| Full Name | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| Alias | AW061165 |
| Introduction | Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.