Recombinant Mouse Activin receptor type-1C (Acvr1c), partial - CD BioSciences

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Recombinant Mouse Activin receptor type-1C (Acvr1c), partial

Recombinant Mouse Activin receptor type-1C (Acvr1c), partial

SPP-00108

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Target Information
Species Mus musculus
Target Name Activin Receptor
UniProt No. Q8K348
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Expressed in interdigital regions in developing limb buds.
Gene Abbr. Acvr1c
Full Name activin A receptor, type IC
Alias ACTR-IC, ACVRLK7, AL, ALK7, Alk
Introduction Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.