Online Inquiry
Recombinant Human Zinc finger FYVE domain-containing protein 9 (ZFYVE9), partial
SPP-04675
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
500 μg | Online Inquiry |
Target Information | |
---|---|
Species | Homo sapiens |
Target Name | Sara |
UniProt No. | O95405 |
Subcellular Location | Cytoplasm, Early endosome membrane |
Tissue Specificity | Ubiquitous. In the brain found primarily in the cerebrovascular smooth muscle cells and reactive astrocytes. |
Gene Abbr. | ZFYVE9 |
Full Name | zinc finger FYVE-type containing 9 |
Alias | MADHIP, NSP, PPP1R173, SARA, SMADIP |
Introduction | Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. |
Product Details | |
---|---|
Product Type | Recombinant Protein |
Storage & Handling | |
---|---|
Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.