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Recombinant Human Transcription factor E2F4 (E2F4)
SPP-01571
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
500 μg | Online Inquiry |
Target Information | |
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Species | Homo sapiens |
Target Name | E2F-4 |
UniProt No. | Q16254 |
Subcellular Location | Nucleus |
Tissue Specificity | Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
Gene Abbr. | E2F4 |
Full Name | E2F transcription factor 4 |
Alias | E2F-4 |
Introduction | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation. |
Product Details | |
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Product Type | Recombinant Protein |
Storage & Handling | |
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Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.