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Recombinant Human Transcription factor 7-like 1 (TCF7L1)
SPP-05012
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | TCF7L1 |
| UniProt No. | Q9HCS4 |
| Subcellular Location | Nucleus |
| Tissue Specificity | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. |
| Gene Abbr. | TCF7L1 |
| Full Name | transcription factor 7 like 1 |
| Alias | TCF-3, TCF3 |
| Introduction | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.