Recombinant Human Presenilin-2 (PSEN2), partial - CD BioSciences

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Recombinant Human Presenilin-2 (PSEN2), partial

Recombinant Human Presenilin-2 (PSEN2), partial

SPP-04382

Size Price
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100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Homo sapiens
Target Name presenilin 2
UniProt No. P49810
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein
Tissue Specificity Isoform 1 is seen in the placenta, skeletal muscle and heart while isoform 2 is seen in the heart, brain, placenta, liver, skeletal muscle and kidney.
Gene Abbr. PSEN2
Full Name presenilin 2
Alias AD3L, AD4, CMD1V, PS2, STM2
Introduction Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.