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Recombinant Human Mitogen-activated protein kinase kinase kinase 13 (MAP3K13), partial
SPP-03605
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | MAP3K13 |
| UniProt No. | O43283 |
| Subcellular Location | Cytoplasm, Membrane, Peripheral membrane protein |
| Tissue Specificity | Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas. |
| Gene Abbr. | MAP3K13 |
| Full Name | mitogen-activated protein kinase kinase kinase 13 |
| Alias | LZK, MEKK13, MLK |
| Introduction | Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.