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Recombinant Human MAP kinase-activated protein kinase 5 (MAPKAPK5)
SPP-03623
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | MAPKAPK-5 |
| UniProt No. | Q8IW41 |
| Subcellular Location | Cytoplasm, Nucleus |
| Tissue Specificity | Expressed ubiquitously. |
| Gene Abbr. | MAPKAPK5 |
| Full Name | MAPK activated protein kinase 5 |
| Alias | MAPKAP-K5, MK-5, MK5, PRAK |
| Introduction | Tumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-induced senescence and phosphorylating p53/TP53. Involved in post-transcriptional regulation of MYC by mediating phosphorylation of FOXO3. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.