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Recombinant Human Lethal (2) giant larvae protein homolog 1 (LLGL1), partial
SPP-03566
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | LLGL1 |
| UniProt No. | Q15334 |
| Subcellular Location | Early endosome membrane, Golgi apparatus, trans-Golgi network membrane, Golgi apparatus membrane, Cell projection, axon, Cytoplasm, cytoskeleton |
| Tissue Specificity | Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease. |
| Gene Abbr. | LLGL1 |
| Full Name | LLGL scribble cell polarity complex component 1 |
| Alias | DLG4, HUGL, HUGL-1, HUGL1, LLGL |
| Introduction | Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.