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Recombinant Human Interleukin-7 receptor subunit alpha (IL7R), partial
SPP-03020
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | IL-7 Receptor |
| UniProt No. | P16871 |
| Subcellular Location | Isoform 1: Cell membrane, Single-pass type I membrane protein; Isoform 3: Cell membrane, Single-pass type I membrane protein; Isoform 4: Secreted |
| Gene Abbr. | IL7R |
| Full Name | interleukin 7 receptor |
| Alias | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| Introduction | IL-7R, or CD127, is often used to characterize regulatory T cells or Tregs. By phenotyping, IL-7R is inversely correlated with the high levels of the hallmark Treg transcription factor FoxP3. So lowered expression of IL-7R on the cell surface along with CD25 and CD4 in addition to FoxP3 internal expression is a major and routinely used technique for Treg cell studies. IL-7R residing on the surface enables enrichment and purification of Treg populations. Antibody to IL-7R is useful for phenotyping, identification, enumeration and purification of Tregs. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.