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Recombinant Human Interleukin-10 protein (IL10) (Active)
SPP-02641
| Size | Price |
| 1 mg | Online Inquiry |
| 500 μg | Online Inquiry |
| 250 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 10 μg | Online Inquiry |
| 2 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | IL-10 |
| UniProt No. | P22301 |
| Subcellular Location | Secreted |
| Tissue Specificity | Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. |
| Gene Abbr. | IL10 |
| Full Name | interleukin 10 |
| Alias | CSIF, GVHDS, IL-10, IL10A, TGIF |
| Introduction | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq]. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Product Form | Lyophilized powder |
| Buffer before Lyophilization | Lyophilized from a 0.2 µm filtered PBS, pH 7.4. |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.