Recombinant Human Histone acetyltransferase KAT2B (KAT2B), partial - CD BioSciences

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Recombinant Human Histone acetyltransferase KAT2B (KAT2B), partial

Recombinant Human Histone acetyltransferase KAT2B (KAT2B), partial

SPP-04105

Size Price
20 μg Online Inquiry
100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Homo sapiens
Target Name PCAF
UniProt No. Q92831
Subcellular Location Nucleus
Tissue Specificity Ubiquitously expressed but most abundant in heart and skeletal muscle.
Gene Abbr. KAT2B
Full Name lysine acetyltransferase 2B
Alias CAF, P/CAF, PCAF
Introduction Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.