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Recombinant Human Histone acetyltransferase KAT2B (KAT2B), partial
SPP-04105
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
500 μg | Online Inquiry |
Target Information | |
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Species | Homo sapiens |
Target Name | PCAF |
UniProt No. | Q92831 |
Subcellular Location | Nucleus |
Tissue Specificity | Ubiquitously expressed but most abundant in heart and skeletal muscle. |
Gene Abbr. | KAT2B |
Full Name | lysine acetyltransferase 2B |
Alias | CAF, P/CAF, PCAF |
Introduction | Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators. |
Product Details | |
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Product Type | Recombinant Protein |
Storage & Handling | |
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Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.