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Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (FLT3LG), partial (Active) (GMP)
SPP-01938
| Size | Price |
| 1 mg | Online Inquiry |
| 100 μg | Online Inquiry |
| 5 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | FLT3 Ligand |
| UniProt No. | P49771 |
| Subcellular Location | Isoform 1: Cell membrane, Single-pass type I membrane protein; Isoform 2: Secreted |
| Gene Abbr. | FLT3LG |
| Full Name | fms related receptor tyrosine kinase 3 ligand |
| Alias | FL, FLG3L, FLT3L |
| Introduction | Flt-3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. Mature mouse Flt-3 Ligand consists of a 161 amino acid (aa) extracellular domain (ECD) with a cytokine-like domain and a juxtamembrane tether region, a 21 aa transmembrane segment, and a 22 aa cytoplasmic tail. Within the ECD, mouse Flt-3 Ligand shares 71% and 81% aa sequence identity with human and rat Flt-3 Ligand, respectively. Mouse and human Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Product Form | Lyophilized powder |
| Buffer before Lyophilization | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.0. |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.