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Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)
SPP-05007
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
500 μg | Online Inquiry |
Target Information | |
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Species | Homo sapiens |
Target Name | TBL1XR1/TBLR1 |
UniProt No. | Q9BZK7 |
Subcellular Location | Nucleus |
Tissue Specificity | Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver. |
Gene Abbr. | TBL1XR1 |
Full Name | TBL1X receptor 1 |
Alias | C21, DC42, IRA1, MRD41, TBLR1 |
Introduction | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. |
Product Details | |
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Product Type | Recombinant Protein |
Storage & Handling | |
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Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.