Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1) - CD BioSciences

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Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)

Recombinant Human F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)

SPP-05007

Size Price
20 μg Online Inquiry
100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Homo sapiens
Target Name TBL1XR1/TBLR1
UniProt No. Q9BZK7
Subcellular Location Nucleus
Tissue Specificity Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver.
Gene Abbr. TBL1XR1
Full Name TBL1X receptor 1
Alias C21, DC42, IRA1, MRD41, TBLR1
Introduction F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.