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Recombinant Human Bone morphogenetic protein receptor type-1B (BMPR1B), partial
SPP-00698
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Homo sapiens |
| Target Name | BMPR-IB/ALK-6 |
| UniProt No. | O00238 |
| Subcellular Location | Cell membrane, Membrane, Single-pass type I membrane protein |
| Gene Abbr. | BMPR1B |
| Full Name | bone morphogenetic protein receptor type 1B |
| Alias | ALK-6, ALK6, AMDD, BDA1D, BDA2 |
| Introduction | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.