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Recombinant Chicken Frizzled-7 (FZD7), partial, Yeast
SPP-02014
| Size | Price |
| 1 mg | Online Inquiry |
| 500 μg | Online Inquiry |
| 200 μg | Online Inquiry |
| 50 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Gallus gallus |
| Target Name | Frizzled-7 |
| UniProt No. | O57329 |
| Subcellular Location | Cell membrane, Multi-pass membrane protein, Endosome membrane, Multi-pass membrane protein |
| Tissue Specificity | Expressed broadly in cranial ectoderm. Also expressed in the developing somites and in other cranial placodes, including the olfactory, lens, otic placodes (lateral half of the vesicle) and epibranchial placodes. |
| Gene Abbr. | FZD7 |
| Full Name | frizzled class receptor 7 |
| Introduction | Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Buffer before Lyophilization | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. Note: If you have any special requirement for the glycerol content, please remark when you place the order. |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.