Recombinant Bovine Gamma-secretase subunit PEN-2 (PSENEN), partial - CD BioSciences

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Recombinant Bovine Gamma-secretase subunit PEN-2 (PSENEN), partial

Recombinant Bovine Gamma-secretase subunit PEN-2 (PSENEN), partial

SPP-04144

Size Price
20 μg Online Inquiry
100 μg Online Inquiry
500 μg Online Inquiry
Target Information
Species Bos taurus
Target Name PEN2
UniProt No. Q5G235
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus, Golgi stack membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein, Membrane, Multi-pass membrane protein
Gene Abbr. PSENEN
Full Name presenilin enhancer, gamma-secretase subunit
Introduction Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity.
Product Details
Product Type Recombinant Protein
Storage & Handling
Storage Temp. Store at -20 °C upon receipt unless otherwise instructed.
Handling Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.