Rebastinib (DCC-2036) - CD BioSciences

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Rebastinib (DCC-2036)

Rebastinib (DCC-2036)

SPC-01847

Rebastinib (DCC-2036)

CAS No. 1020172-07-9

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Bcr-Abl inhibitor

Description
Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1.
Product Details
CAS No. CAS No. 1020172-07-9
Description Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1.
Formula C30H28FN7O3
Molecular Weight 553.59
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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