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R547
SPC-01818
CAS No. 741713-40-6
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 2 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
CDK inhibitor
| Description |
|---|
| R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 741713-40-6 |
| Description | R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1. |
| Formula | C18H21F2N5O4S |
| Molecular Weight | 441.45 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Ro 4584820 |
| SMILES | COC1=C(C(=C(C=C1)F)F)C(=O)C2=CN=C(N=C2N)NC3CCN(CC3)S(=O)(=O)C |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.