Quisinostat (JNJ-26481585) 2HCl - CD BioSciences

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Quisinostat (JNJ-26481585) 2HCl

Quisinostat (JNJ-26481585) 2HCl

SPC-01816

Quisinostat (JNJ-26481585) 2HCl

CAS No. 875320-31-3

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10 mM (1 mL in DMSO) Online Inquiry
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HDAC inhibitor

Description
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
Product Details
CAS No. CAS No. 875320-31-3
Description Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
Formula C21H28Cl2N6O2
Molecular Weight 467.39
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO.Cl.Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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