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Quisinostat (JNJ-26481585) 2HCl
SPC-01816
CAS No. 875320-31-3
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
5 mg | Online Inquiry |
10 mg | Online Inquiry |
50 mg | Online Inquiry |
200 mg | Online Inquiry |
Bulk Size | Online Inquiry |
HDAC inhibitor
Description |
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Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2. |
Product Details | |
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CAS No. | CAS No. 875320-31-3 |
Description | Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2. |
Formula | C21H28Cl2N6O2 |
Molecular Weight | 467.39 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO.Cl.Cl |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.