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Purmorphamine
SPC-01799
CAS No. 483367-10-8
| Size | Price |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 1 g | Online Inquiry |
| Bulk Size | Online Inquiry |
Hedgehog/Smoothened agonist ; Autophagy inhibitor
| Description |
|---|
| Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM. Purmorphamine can reduce both basal and induced autophagy. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 483367-10-8 |
| Description | Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM. Purmorphamine can reduce both basal and induced autophagy. |
| Formula | C31H32N6O2 |
| Molecular Weight | 520.62 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | N/A |
| SMILES | C1CCC(CC1)N2C=NC3=C(N=C(N=C32)OC4=CC=CC5=CC=CC=C54)NC6=CC=C(C=C6)N7CCOCC7 |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.