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PTP1B siRNA I
SPR-00964
| Size | Price |
| 1 Unit | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | PTP1B |
| Gene Abbr. | PTPN1 |
| Gene ID | 5770 |
| Full Name | protein tyrosine phosphatase non-receptor type 1 |
| Alias | PTP1B |
| Introduction | Three distinct types of phosphoinositide 3-kinases (PI3K) have been characterized. Unlike other PI3Ks, PI3K class III catalyzes the phosphorylation of phosphatidylinositol at the D3 position, producing phosphatidylinositol-3-phosphate (PIP3). PI3K class III is the mammalian homolog of Vps34, first identified in yeast. PI3K class III interacts with the regular subunit p150, the mammalian homolog of Vps15, which regulates cellular membrane association through myristoylation. PIP3 recruits several proteins with FYVE or PX domains to membranes regulating vesicular transport and protein sorting. Moreover, PI3K class III has been shown to regulate autophagy, trimeric G-protein signaling, and the mTOR nutrient-sensing pathway. |
| Usage | |
|---|---|
| Application | RNA interference |
| Reactivity | |
| Storage & Handling | |
|---|---|
| Storage Buffer | The siRNA product is supplied in RNAse-free water. |
| Storage Temp. | Aliquot and store at -20 °C. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.