PSD95 Antibody - CD BioSciences

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PSD95 Antibody

PSD95 Antibody

SPA-09269

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Target Information
Target Name PSD95
Gene Abbr. DLG4
Gene ID 1742
Full Name discs large MAGUK scaffold protein 4
Alias MRD62, PSD95, SAP-90, SAP90
Introduction Postsynaptic Density protein 95 (PSD95) is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. These family members consist of an amino-terminal variable segment followed by three PDZ domains, an SH3 domain, and an inactive guanylate kinase (GK) domain. PSD95 is a scaffolding protein involved in the assembly and function of the postsynaptic density complex. PSD95 participates in synaptic targeting of AMPA receptors through an indirect manner involving Stargazin and related transmembrane AMPA receptor regulatory proteins (TARPs). It is implicated in experience-dependent plasticity and plays an indispensable role in learning. Mutations in PSD95 are associated with autism.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 7E3
Immunogen Recombinant protein specific to the Full length rat PSD95 protein.
Source/Purification Antibody is produced by immunizing animals with recombinant protein specific to the full length rat PSD95 protein.
Usage
Application WB, IF
Dilutions Western Blot (1:1000)
MW(KDa) 95
Reactivity Human, Mouse, Rat
Sensitivity Endogenous
Specificity It recognizes endogenous levels of total PSD95 protein.
Storage & Handling
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide.
Preservative Less than 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Do not aliquot the antibody.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.