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PRKDC (+/-) Cell Line
SPL-02816
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| PRKDC (+/-) |
| Target Information | |
|---|---|
| Target Name | DNA-PKcs |
| Gene Abbr. | PRKDC |
| Gene ID | 5591 |
| Full Name | protein kinase, DNA-activated, catalytic subunit |
| Alias | DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1 |
| Species | Human |
| Genomic Locus | 8q11 |
| Introduction | This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]. |
| Product Details | |
|---|---|
| Cell Line Model | NALM-6 |
| Genotype | PRKDC (+/-) |
| Description | PRKDC (+/-) |
| Parental ATCC ID | DSMZ: ACC 128 |
| Disease | Acute lymphoblastic leukemia |
| Tissue | B-Cell |
| Gender | Male |
| Key Endogenous Mutations | CDKN2A, CDKN2a(p14), MSH2, NRAS |
| CVT Selection Condition | G418 resistant - 1.0 mg/mL |
| Cell Number | 1x10^6 |
| Handling Specifications | |
|---|---|
| Revival | Cells are cultured as a suspension at 37°C in a humidified atmosphere with 5% CO2. Cells should be passaged every 3-5 days. Maintain at 1.0-3.0 x 106 cells/ml, splitting approximately 1:6-1:10 |
| Culture Medium | RPMI 1640 including 2 mM L-glutamine and 25 mM sodium bicarbonate, supplemented with 10% FBS. |
| Growth Properties | Cells are cultured as a suspension at 37°C in a humidified atmosphere with 5% CO2. Cells should be passaged every 3-5 days. Maintain at 1.0-3.0 x 106 cells/ml, splitting approximately 1:6-1:10 |
| Freeze Medium | Complete growth media 40% + USDA approved FBS 50% + DMSO 10% |
| Biosafety Level | BSL-1 |
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.