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Pref-1/DLK1/FA1 Antibody
SPA-02925
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | DLK1 |
| Gene Abbr. | DLK1 |
| Gene ID | 8788 |
| Full Name | delta like non-canonical Notch ligand 1 |
| Alias | DLK, DLK-1, Delta1, FA1, PREF1 |
| Introduction | This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 3A10 |
| Isotype | IgG1 |
| Immunogen | Purified recombinant fragment of human DLK1 expressed in E. coli. |
| Usage | |
|---|---|
| Application | WB, ELISA, FC, IF |
| Dilutions | Western Blot (1:500-1:2000); ELISA (1:10000); Flow Cytometry (1:200-1:400); Immunofluorescence (1:200-1:1000) |
| Reactivity | Human |
| Storage & Handling | |
|---|---|
| Storage Buffer | Ascites. |
| Preservative | 0.03% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.