PPARγ Antibody - CD BioSciences

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PPARγ Antibody

PPARγ Antibody

SPA-09221

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Target Information
Target Name PPAR
Gene Abbr. PPARG
Gene ID 5468
Full Name peroxisome proliferator activated receptor gamma
Alias CIMT1, GLM1, NR1C3, PPARG1, PPARG2
Introduction Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the ligand-activated nuclear receptor superfamily and functions as a transcriptional activator. PPARγ is preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipid metabolism PPARγ also modulates insulin sensitivity, cell proliferation and inflammation. PPARγ transcriptional activity is inhibited by MAP kinase phosphorylation of PPARγ at Ser84.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. D8I3Y
Immunogen Synthetic peptide corresponding to residues surrounding His494 of human PPARγ protein.
Source/Purification Antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His494 of human PPARγ protein.
Usage
Application WB, IP
Dilutions Western Blot (1:1000); Immunoprecipitation (1:50)
MW(KDa) 53, 57
Reactivity Human, Mouse
Sensitivity Endogenous
Specificity It recognizes endogenous levels of total PPARγ protein.
Storage & Handling
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide.
Preservative Less than 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Do not aliquot the antibody.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.