Posaconazole - CD BioSciences

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Posaconazole

Posaconazole

SPC-01751

Posaconazole

CAS No. 171228-49-2

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P450 (e.g. CYP17) inhibitor

Description
Posaconazole (SCH56592) is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
Product Details
CAS No. CAS No. 171228-49-2
Description Posaconazole (SCH56592) is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
Formula C37H42F2N8O4
Molecular Weight 700.78
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms SCH56592
SMILES CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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