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PLX7904
SPC-01740
CAS No. 1393465-84-3
| Size | Price |
| 5 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Raf inhibitor
| Description |
|---|
| PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1393465-84-3 |
| Description | PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. |
| Formula | C24H22F2N6O3S |
| Molecular Weight | 512.53 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | PB04 |
| SMILES | CCN(C)S(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CN=C(N=C4)C5CC5)F |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.