NCBI Accession #
NP_193123.2
NCBI GenBank Nucleotide #
NM_117461.2
NCBI Official Full Name
Werner syndrome-like exonuclease
NCBI Official Symbol
WRNEXO
NCBI Official Synonym Symbols
ATWEX; ATWRNEXO; EXONUCLEASE; F18A5.260; F18A5_260; Werner syndrome-like exonuclease; WEX
NCBI Protein Information
Werner syndrome-like exonuclease
NCBI Summary
Encodes a protein with homology to the exonuclease domain of hWRN-p of human protein Werner Syndrome Exonuclease (WEX). Forms a complex with the heterodimeric factor Ku. The interaction with KU stimulates WEX exonuclease activity.
UniProt Synonym Gene Names
WRNEXO
UniProt Protein Name
Werner Syndrome-like exonuclease
UniProt Primary Accession #
Q84LH3
UniProt Secondary Accession #
Q6QPM3; Q9FT68; Q9SVM6
UniProt Related Accession #
Q84LH3
UniProt Comments
Exonuclease that digests recessed strands of DNA duplexes in the 3' to 5' direction but hardly single-stranded DNA or blunt-ended duplexes. Also able to digest 3'-protruding strands and 3'-recessed strand termini of duplexes containing mismatched bases.